Incidence and associated risk factors for recurrence of Hepatorenal syndrome-acute kidney injury in Patients with Cirrhosis

Background and Aim: Acute kidney injury (AKI) in patients with cirrhosis results high short-term mortality. HRS accounts for approximately 25% of cases prerenal AKI. Recurrence HRS-AKI after treatment is variable, ranging from 25-50% different studies. There limited literature on the factors that predict recurrence HRS-AKI. The aim to assess incidence predicting liver cirrhosis. Also, evaluate response acute hepatorenal syndrome currently available treatment. Methods: Prospective observational study. Patients diagnosed were recruited applying inclusion exclusion criteria treated at discretion physician. divided into complete partial responders according their who showed a followed up. primary outcome was 3-month follow-up. secondary identification risk Results: A total 93 enrolled Sixty-four (68.81%) had During follow-up, recurred 11 (21.57%) patients. mean value MAP admission significantly higher without (79.5 ± 7.34) than (74.86 4.5) (p-value= 0.003). difference between last visit (1.6 3.96) -recurrence (-2.82 2) 0.0008). received midodrine follow-up did not receive (2.44 3.42 vs. -1.06 3.44) 0.0002). Conclusions: protect against Administration increases may play role prevention However, large, randomized trial needed further validation.